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Bernard van Orley, Barend van Orley, Bernaert van Orley ou encore Barend van Brussel est un peintre de la Renaissance né à Bruxelles vers 1488 et mort à Bruxelles le 6 janvier 1541. Peintre de sujets religieux et de portraits, auteur de cartons de tapisseries et de vitraux, il fait partie des peintres qui dans le nord de l'Europe de l'ouest marqueront le passage du gothique à la renaissance.
Bernard van Orley (between 1487 and 1491 – 6 January 1541), also called Barend or Barent van Orley, Bernaert van Orley or Barend van Brussel, was a leading artist in Dutch and Flemish Renaissance painting, though he was at least as active as a leading designer of Brussels tapestry and, at the end of his life, stained glass. Although he never visited Italy, he belongs to the group of Italianizing Flemish painters called the Romanists, who were influenced by Italian Renaissance painting, in his case especially by Raphael.